Causes or Risk Factors of Chronic Kidney Disease (CKD)

Most kidney diseases attack the nephrons, causing them to lose their filtering capacity. Damage to the nephrons may sometimes happen quickly, for example as the result of an injury or poisoning. But most kidney diseases destroy the nephrons slowly and silently (chronic kidney disease). Only after years or even decades does the damage become apparent. Most kidney diseases attack both kidneys simultaneously.

Diabetes mellitus, hypertension, glomerulonephritis, and polycystic kidney disease are the most common causes of chronic kidney disease.

Content last updated
  1. Fauci A, Braunwald E, Kasper DL et al.: Harrison´s Principles of Internal Medicine, 17th Edition, 2008
  2. National Kidney Foundation (last visited 30.03.2010)